ITGA3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ITGA3 wild-type allele is located in the vicinity of 17q21.33 and is approximately 35 kb in length. This allele, which encodes integrin alpha-3 protein, is involved in cell-matrix adhesion and invadopodia formation. Mutation of the gene is associated with junctional epidermolysis bullosa 7 including interstitial lung disease and nephrotic syndrome.

**Synonyms:** - Alpha 3 Subunit of VLA-3 Receptor Gene - Antigen Identified By Monoclonal Antibody J143 Gene - CD49C - FRP-2 - GAP-B3 - GAPB3 - ILNEB - Integrin Alpha 3 Gene - Integrin Subunit Alpha 3 wt Allele - Integrin, Alpha 3 (Antigen CD49C, Alpha 3 Subunit of VLA-3 Receptor) Gene - Integrin, Alpha-3 Gene - JEB7 - MSK18 - VCA-2 - VL3A - VLA3a - Very Late Activation Protein 3 Receptor, Alpha-3 Subunit Gene - Very Late Activation Receptor Subunit Alpha-3 Gene