Integral Membrane Protein 2B

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Integral membrane protein 2B (266 aa, ~30 kDa) is encoded by the human ITM2B gene. This protein is involved in steric hinderance of amyloid-beta precursor protein cleavage by both beta- and gamma-secretases.

**Synonyms:** - Bri - ITM2B - Immature BRI2 - Protein E25B - Transmembrane Protein BRI - imBRI2