GALNS wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GALNS wild-type allele is located in the vicinity of 16q24.3 and is approximately 43 kb in length. This allele, which encodes N-acetylgalactosamine-6-sulfatase protein, is involved in the removal of 6-sulfate groups from chondroitin sulfate and keratan sulfate. Mutation of the gene is associated with mucopolysaccharidosis IVA (Morquio syndrome A).

**Synonyms:** - GALNAC6S - GAS - GalN6S - Galactosamine (N-Acetyl)-6-Sulfatase wt Allele - Galactosamine (N-Acetyl)-6-Sulfate Sulfatase Gene - MPS4A