DPP6 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DPP6 wild-type allele is located in the vicinity of 7q36.2 and is approximately 1146 kb in length. This allele, which encodes A-type potassium channel modulatory protein DPP6, plays a role in the regulation of neuronal excitability mediated by voltage-activated A-type potassium ion channels. Mutation of the gene is associated with paroxysmal familial ventricular fibrillation 2 and autosomal dominant intellectual developmental disorder 33. Polymorphism in this gene may be associated with variable susceptibility to amyotrophic lateral sclerosis.

**Synonyms:** - DPL1 - DPPX - Dipeptidyl Peptidase 6 Gene - Dipeptidyl Peptidase Like 6 wt Allele - Dipeptidyl-Peptidase 6 Gene - Dipeptidylpeptidase 6 Gene - Dipeptidylpeptidase VI Gene - MRD33 - VF2