Pineoblastoma, RB1-Altered

**Semantic type:** Neoplastic Process

**Definition:** Pineoblastoma characterized by alterations in RB1 gene. It may develop in the setting of congenital retinoblastoma, also known as trilateral retinoblastoma. It affects young children and is associated with a dismal prognosis.

**Synonyms:** - PB, RB1-Altered - PB-RB1 - Pineoblastoma-RB1