ASTCT CRS Grade 3

**Semantic type:** Quantitative Concept

**Definition:** Fever (greater than or equal to 38C) with hypotension requiring 1 vasopressor with or without vasopressin and/or hypoxia requiring high-flow nasal cannula (greater than 6 L/minute), face mask, nonrebreather mask, or Venturi mask not attributable to any other cause.