Farnesyl Transferase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits protein farnesyltransferase, an enzyme that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine. Protein farnesyltransferase is involved in Ras-mediated post-translational modification. Inhibition of protein farnesyltransferase may inhibit the oncogenic activity of Ras.

**Synonyms:** - FTI - Farnesyl Transferase Inhibitors - Farnesyltransferase Inhibitors - Protein Farnesyltransferase Inhibitor - Protein Farnesyltransferase Inhibitors