Human Milk Oligosaccharides-based Formulation PBCLN-010

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable formulation containing human milk oligosaccharides (HMOs), with potential microbiome-enhancing, protective and immunomodulating activities. Upon oral administration, HMO-based formulation PBCLN-010 provides HMOs to the unhealthy, altered gut microbiome and enables the growth of diverse beneficial bacteria in the gut. This improves the immune system, suppresses inflammation, and enhances intestinal barrier function. This may lower the risk of GI antibiotic-resistant bacterial infections, bacteremia and graft-versus-host disease (GvHD) in patients undergoing solid organ and allogeneic stem cell transplantation.

**Synonyms:** - PBCLN 010 - PBCLN-010 - PBCLN010