Autologous Anti-CD19 CAR T Cells KITE-197

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous T-lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T-cells KITE-197 specifically recognize and kill tumor cells expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.

**Synonyms:** - Autologous CAR T-cells KITE-197 - Autologous CAR-T Cells KITE-197 - KITE 197 - KITE-197 - KITE197