NUDT15 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NUDT15 wild-type allele is located in the vicinity of 13q14.2 and is approximately 15 kb in length. This allele, which encodes nucleotide triphosphate diphosphatase NUDT15, plays a role in the hydrolysis of nucleoside triphosphates and their oxidized forms. Variant haplotypes of the gene are associated with poor metabolism of thiopurines 2.

**Synonyms:** - 8-Oxo-dGTPase NUDT15 Gene - FLJ10956 - MTH2 - NUDT15D - Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 Gene - Nudix Hydrolase 15 wt Allele - Probable 7,8-Dihydro-8-Oxoguanine Triphosphatase NUDT15 Gene - Probable 8-Oxo-dGTP Diphosphatase NUDT15 Gene