EWSR1/TFCP2 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal rearrangement involving the long arms of chromosomes 22 (22q) and 12 (12q) that fuses the first 6 exons of the EWSR1 gene upstream of exon 2 of the TFCP2 gene. This fusion is associated with a subset of rhabdomyosarcomas characterized by TFCP2 rearrangement and poor prognosis.

**Synonyms:** - EWSR1-TFCP2 Fusion Gene - EWSR1::TFCP2 Fusion Gene - TFCP2/EWSR1 Fusion Gene