FUS/TFCP2 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal rearrangement involving the short arm of chromosome 16 (16p) and the long arm of chromosome 12 (12q) that fuses the first 6 exons of the FUS gene in frame with exon 2 of the TFCP2 gene. This fusion is associated with a subset of rhabdomyosarcomas characterized by TFCP2 rearrangement and poor prognosis.

**Synonyms:** - FUS-TFCP2 Fusion Gene - FUS::TFCP2 Fusion Gene - TFCP2/FUS Fusion Gene