H-ras Antisense Oligodeoxynucleotide ISIS 2503

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the oncogene H-Ras. ISIS 2503 selectively inhibits the expression of H-Ras, and may inhibit the growth of some Ras-dependent tumor cells. (NCI04)

**Synonyms:** - H-RAS Antisense - ISIS 2503 - ISIS 2503 - ISIS-2503 - ISIS-2503 - ISIS2503