Tyrphostin A9

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A member of the tyrphostin family of tyrosine kinase inhibitors that exhibits anti-proliferative activity by selectively inhibiting the platelet-derived growth factor receptor tyrosine kinase. It inhibits phosphorylation, uncouples oxidative phosphorylation and induces apoptosis and cell growth arrest in certain cancer cell lines. (NCI)

**Synonyms:** - AG 17