LAMA2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LAMA2 wild-type allele is located in the vicinity of 6q22.33 and is approximately 633 kb in length. This allele, which encodes laminin subunit alpha-2 protein, plays a role in laminin assembly. Mutations in the gene are associated with both congenital merosin-deficient muscular dystrophy and autosomal recessive limb-girdle muscular dystrophy 23.

**Synonyms:** - Congenital Muscular Dystrophy Gene - LAMM - Laminin 2, Heavy Chain Gene - Laminin Subunit Alpha 2 wt Allele - Laminin, Alpha 2 Gene - Laminin, Alpha-2 Gene - MDC1A - Merosin Gene