LDLRAP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LDLRAP1 wild-type allele is located in the vicinity of 1p36.11 and is approximately 47 kb in length. This allele, which encodes low density lipoprotein receptor adapter protein 1, is involved in low density lipoprotein receptor (LDLR)-dependent metabolism of cholesterol and low density lipoprotein particles. Mutation of the gene is associated with autosomal recessive hypercholesterolemia.

**Synonyms:** - ARH - ARH1 - ARH2 - Autosomal Recessive Hypercholesterolemia Gene - DKFZP586D0624 - DKFZp586D0624 - FHCB1 - FHCB2 - FHCL4 - LDL Receptor Adaptor Protein Gene - Low Density Lipoprotein Receptor Adaptor Protein 1 wt Allele - MGC34705