Zimislecel

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of allogeneic human stem cell-derived, fully differentiated functional pancreatic islet cells, that can be used for islet cell transplantation for the treatment of type 1 diabetes mellitus. Upon infusion into the hepatic portal vein, zimislecel may replace and restore pancreatic islet cells, which are destroyed in patients with type 1 diabetes. These cells may restore pancreatic islet cell function, produce insulin and may regulate blood glucose levels.

**Synonyms:** - Allogeneic Human Stem Cell-derived Beta Cells VX-880 - Allogeneic Human Stem Cell-derived Islet Cells VX-880 - Allogeneic Human Stem Cell-derived Pancreatic Islet Cells VX-880 - Allogeneic Stem Cell-derived Fully Differentiated Insulin-producing Pancreatic Islet Cells VX-880 - STx 02 - STx-02 - STx02 - VX 880 - VX-880 - VX880 - ZIMISLECEL