CBLIF wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CBLIF wild-type allele is located in the vicinity of 11q12.1 and is approximately 16 kb in length. This allele, which encodes cobalamin binding intrinsic factor protein, plays a role in recognition of cobalamin in the digestive tract and targeting it for endocytosis. Mutations in the gene are associated with congenital pernicious anemia due to intrinsic factor deficiency.

**Synonyms:** - Cobalamin Binding Intrinsic Factor wt Allele - GIF - Gastric Intrinsic Factor (Vitamin B Synthesis) Gene - IF - IFMH - INF - TCN3