Prostaglandin Reductase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Prostaglandin reductase 1 (329 aa, ~36 kDa) is encoded by the human PTGR1 gene. This protein plays a role in the metabolism of eicosanoids, including the reduction of leukotriene B4 to 12-oxo-leukotriene B4.

**Synonyms:** - 15-Oxoprostaglandin 13-Reductase - D3T-Inducible Gene 1 Protein - DIG-1 - Dithiolethione-Inducible Gene 1 Protein - EC 1.3.1.48 - EC 1.3.1.74 - Leukotriene B4 12-Hydroxydehydrogenase - NAD(P)H-Dependent Alkenal/One Oxidoreductase - NADP-Dependent Leukotriene B4 12-Hydroxydehydrogenase - PRG-1 - PTGR1