MAT1A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAT1A wild-type allele is located in the vicinity of 10q22.3 and is approximately 18 kb in length. This allele, which encodes S-adenosylmethionine synthase isoform type-1 protein, plays a role in S-adenosyl-L-methionine biosynthesis. Mutation of the gene is associated with hypermethioninemia due to methionine adenosyltransferase deficiency.

**Synonyms:** - AMS1 - AdoMet Synthetase 1 Gene - MAT - MATA1 - Methionine Adenosyltransferase 1A wt Allele - Methionine Adenosyltransferase I, Alpha Gene - S-Adenosylmethionine Synthetase Gene - SAMS - SAMS, Liver-Specific Gene - SAMS1