S-Adenosylmethionine Synthase Isoform Type-1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** S-adenosylmethionine synthase isoform type-1 (395 aa, ~44 kDa) is encoded by the human MAT1A gene. This protein is involved in catalyzing the transfer of the adenosyl moiety of ATP to methionine, which yields S-adenosylmethionine, diphosphate (PPi) and phosphate (Pi).

**Synonyms:** - AdoMet Synthase 1 - AdoMet Synthetase 1 - EC 2.5.1.6 - MAT 1 - MAT-I/III - MAT1A - Methionine Adenosyltransferase 1 - Methionine Adenosyltransferase 1A - Methionine Adenosyltransferase I/III - S-Adenosylmethionine Synthetase