Protein Phosphatase 2A Subunit Gene

**Semantic type:** Gene or Genome

**Definition:** The Protein Phosphatase 2A Subunit Genes encodes 3 subunits (A, B, and C) of Protein Phosphatase 2A (PP2A) holoenzyme, a heterotrimeric serine/threonine phosphatase. The structural A subunit and the catalytic C subunit form a catalytic core, while substrate specificity is directed by the B subunit. PP2A exerts regulatory control over the initiation of DNA replication and has a particularly complex set of regulatory subunits controlling its function and localization.