OAT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human OAT wild-type allele is located in the vicinity of 10q26.13 and is approximately 22 kb in length. This allele, which encodes ornithine aminotransferase, mitochondrial protein, is involved in the reversible transamination of ornithine to glutamate semialdehyde. Mutations in the gene are associated with gyrate atrophy.

**Synonyms:** - GACR - Gyrate Atrophy Gene - HOGA - OATASE - OKT - Ornithine Aminotransferase Precursor Gene - Ornithine Aminotransferase wt Allele