CALHM1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CALHM1 wild-type allele is located in the vicinity of 10q24.33 and is approximately 6 kb in length. This allele, which encodes calcium homeostasis modulator protein 1, plays a role in voltage-gated and calcium-activated ion channel activity, taste perception and modulating the processing of amyloid-beta precursor protein. Polymorphism at this locus may be associated with susceptibility to late-onset Alzheimer disease.

**Synonyms:** - Calcium Homeostasis Modulator 1 wt Allele - FAM26C - Family With Sequence Similarity 26, Member C Gene