ROS1 Inhibitor JYP0322

**Semantic type:** Pharmacologic Substance

**Definition:** An orally available selective inhibitor of the receptor tyrosine kinase c-ros oncogene 1 (ROS1), with potential antineoplastic activity. Upon oral administration, ROS1 inhibitor JYP0322 targets, binds to and inhibits ROS1. This inhibits proliferation of ROS1-driven tumor cells. ROS1, overexpressed, rearranged and/or mutated in certain cancer cells, plays a key role in cell growth and survival of various types of cancer cells.

**Synonyms:** - JYP 0322 - JYP-0322 - JYP0322