Fibroblast Growth Factor

**Semantic type:** Amino Acid, Peptide, or Protein|Biologically Active Substance

**Definition:** A family of structurally-related growth factors with high affinity for heparin. These proteins modulate cell proliferation, angiogenesis, wound healing, embryogenesis and paracrine signaling pathways. Fibroblast growth factors (FGF) stimulate signal transduction through binding to specific members of the fibroblast growth factor receptors (FGFR) family tyrosine kinases.

**Synonyms:** - DNA Synthesis Factor - ECGF - Endothelial Cell Growth Factor - FGF - FGF Family - Fibroblast Growth Factor Family - Fibroblast Growth Regulatory Factor