PINK1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PINK1 wild-type allele is located in the vicinity of 1p36.12 and is approximately 18 kb in length. This allele, which encodes Serine/threonine-protein kinase PINK1, mitochondrial protein, plays a role in prevention of mitochondrial dysfunction. Mutations in the gene are associated with early onset Parkinson disease 6.

**Synonyms:** - BRPK - PARK6 - PTEN Induced Kinase 1 wt Allele - PTEN Induced Putative Kinase 1 Gene - Parkinson Disease (Autosomal Recessive) 6 Gene - Protein Kinase BRPK Gene