Augmented HyperCVAD/Pegaspargase Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of cyclophosphamide, vincristine, doxorubicin and dexamethasone, administered on a hyperfractionated schedule and with intensified doses of vincristine and dexamethasone, plus pegaspargase that is used to treat adult acute lymphoblastic leukemia (ALL).

**Synonyms:** - Augmented Hyper-CVAD Plus Pegaspargase Regimen - Augmented HyperCVAD Plus Pegaspargase Regimen - Augmented Hyperfractionated Cyclophosphamide-Vincristine-Adriamycin-Dexamethasone Plus Pegaspargase Regimen