Methylated DNA Immunoprecipitation Sequencing

**Semantic type:** Molecular Biology Research Technique

**Definition:** A strategy to obtain DNA sequences from methylated sites. Genomic DNA is randomly sheared by sonication and immunoprecipitated with a monoclonal antibody that specifically recognizes 5-methylcytidine. The DNA fragments are then isolated and sequenced.

**Synonyms:** - MeDIP-Seq - MeDIP-Seq