PRKRA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRKRA wild-type allele is located in the vicinity of 2q31.2 and is approximately 20 kb in length. This allele, which encodes interferon-inducible double-stranded RNA-dependent protein kinase activator A protein, plays a role in RNA-induced silencing and the activation of interferon-inducible eIF2alpha kinase (EIF2AK2) activity. Mutation of the gene is associated with dystonia 16.

**Synonyms:** - DYT16 - HSD-14 - HSD14 - PACT - Protein Activator of Interferon Induced Protein Kinase EIF2AK2 wt Allele - Protein Activator of Interferon-Induced Protein Kinase Gene - Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Gene - Protein Kinase, Interferon-Inducible Double-Stranded RNA-Dependent Activator Gene - RAX