QDPR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human QDPR wild-type allele is located in the vicinity of 4p15.32 and is approximately 52 kb in length. This allele, which encodes dihydropteridine reductase protein, is involved in the NADH-mediated reduction of quinonoid dihydrobiopterin yielding tetrahydrobiopterin. Mutations in the gene are associated with BH4-deficient hyperphenylalaninemia C.

**Synonyms:** - DHPR - HDHPR - PKU2 - Quinoid Dihydropteridine Reductase wt Allele - SDR33C1 - Short Chain Dehydrogenase/Reductase Family 33C, Member 1 Gene