RNASEH2B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RNASEH2B wild-type allele is located in the vicinity of 13q14.3 and is approximately 114 kb in length. This allele, which encodes ribonuclease H2 subunit B protein, is involved in the regulation of ribonuclease activity during DNA replication and the degradation of RNA and RNA:DNA hybrids. Mutations in the gene are associated with Aicardi-Goutieres syndrome 2.

**Synonyms:** - AGS2 - Aicardi-Goutieres Syndrome 2 Gene - DLEU8 - Deleted In Lymphocytic Leukemia 8 Gene - FLJ11712 - Ribonuclease H2 Subunit B wt Allele - Ribonuclease H2, Subunit B Gene