Leukemia Inhibitory Factor

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** Leukemia inhibitory factor (202 aa, ~22 kDa) is encoded by the human LIF gene. This protein plays a role in the positive regulation of neuronal cell differentiation and the induction of hematopoietic differentiation in normal and myeloid leukemia cells.

**Synonyms:** - Cholinergic Differentiation Factor - D Factor - D-Factor - Differentiation Inhibitory Activity - Differentiation Stimulating Factor - Differentiation-Stimulating Factor - Hepatocyte-Stimulating Factor III - Human Interleukin in DA Cells - LIF - Leukemia-Inhibitory Factor - MLPLI - Melanoma-Derived LPL Inhibitor