EWSR1/PBX3 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from chromosomal translocation t(9;22)(q33;q12) that fuses intron 9 of the EWSR1 gene to intron 4 of the PBX3 gene. This fusion is associated with retroperitoneal leiomyoma and a small subset of myoepitheliomas, including intraosseous and skin syncytial myoepitheliomas.

**Synonyms:** - EWS RNA-Binding Protein 1/PBX Homeobox 3 Fusion Gene - EWS RNA-Binding Protein 1::PBX Homeobox 3 Fusion Gene - EWSR1-PBX3 Fusion Gene - EWSR1::PBX3 Fusion Gene