Familial Adult Myoclonic Epilepsy 1

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant condition caused by mutation(s) in the SAMD12 gene, encoding sterile alpha motif domain-containing protein 12. It is characterized by adult onset cortical myoclonic tremor and epilepsy.

**Synonyms:** - FAME1 - FCMTE1 - Familial Cortical Myoclonic Tremor Associated with Epilepsy-1