PEAK1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PEAK1 wild-type allele is located in the vicinity of 15q24.3 and is approximately 320 kb in length. This allele, which encodes inactive tyrosine-protein kinase PEAK1 protein, plays a role in the mediation of EGFR signaling and the modulation of focal adhesion elongation. A frameshift mutation may be associated with childhood B-cell acute lymphoblastic leukemia.

**Synonyms:** - KIAA2002 - NKF3 Kinase Family Member Gene - Pseudopodium Enriched Atypical Kinase 1 wt Allele - SGK269 - sgk269