ASMTL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ASMTL wild-type allele is located in the vicinity of both Xp22.3 and Yp11.3 and is approximately 51 kb in length. This allele, which encodes probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein, plays a role in methyltransferase activity and the hydrolysis of dTTP, UTP, CTP and modified pyrimidines. Point mutations in this gene may be associated with childhood B-cell acute lymphoblastic leukemia.

**Synonyms:** - ASMTLX - ASMTLY - ASTML - Acetylserotonin Methyltransferase-Like ASTML, X-Linked Gene - Acetylserotonin Methyltransferase-Like Gene - Acetylserotonin Methyltransferase-Like, Y-Linked Gene - Acetylserotonin N-Methyltransferase-Like Gene - Acetylserotonin O-Methyltransferase Like wt Allele - N-Acetylserotonin O-Methyltransferase-Like Protein Gene