Autologous Anti-CD22 CAR-T Cells CLIC-2201

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD22, with potential antineoplastic activity. Upon administration, autologous anti-CD22 CAR-T cells CLIC-2201 recognize and kill CD22-expressing tumor cells. CD22, a B-lineage-restricted, transmembrane phosphoglycoprotein, is expressed on malignant B-cells.

**Synonyms:** - Autologous Anti-CD22 CAR T Cells CLIC-2201 - Autologous CD22-targeting CAR T-cells CLIC-2201 - CLIC 2201 - CLIC-2201 - CLIC2201