Hypermutated/MMRd Endometrial Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** An endometrial carcinoma characterized by mismatch repair (MMR) deficiency caused by inactivating methylation or less frequently mutation of an MMR gene (MLH1, PMS2, MSH2, or MSH6).

**Synonyms:** - Hypermutated/MMRd Endometrial Cancer - Mismatch Repair-Deficient Endometrial Cancer - Mismatch Repair-Deficient Endometrial Carcinoma