POLEm Endometrial Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** An endometrial carcinoma characterized by mutations in the exonuclease domain of the DNA polymerase epsilon (POLE) gene that result in an ultra-mutated tumor phenotype.

**Synonyms:** - POLE-Ultra-Mutated Endometrial Cancer - POLE-Ultra-Mutated Endometrial Carcinoma - POLE-Ultramutated Endometrial Cancer - POLE-Ultramutated Endometrial Carcinoma - POLEm Endometrial Cancer