SCNN1G wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SCNN1G wild-type allele is located in the vicinity of 16p12.2 and is approximately 34 kb in length. This allele, which encodes amiloride-sensitive sodium channel subunit gamma protein, plays a role in the reabsorption of sodium in kidney, colon, lung and sweat glands. Mutations in the gene are associated with Liddle syndrome type 2, bronchiectasis with or without elevated sweat chloride type 3 and autosomal recessive pseudohypoaldosteronism type 1B3.

**Synonyms:** - Amiloride-Sensitive Epithelial Sodium Channel Gamma Subunit Gene - Amiloride-Sensitive Sodium Channel Gamma-Subunit Gene - BESC3 - ENaC Gamma Subunit Gene - ENaCg - ENaCgamma - LDLS2 - PHA1 - PHA1B3 - SCNEG - Sodium Channel Epithelial 1 Gamma Subunit Gene - Sodium Channel Epithelial 1 Subunit Gamma wt Allele - Sodium Channel, Epithelial 1, Gamma Subunit Gene - Sodium Channel, Epithelial, Gamma Subunit Gene - Sodium Channel, Non Voltage Gated 1 Gamma Subunit Gene - Sodium Channel, Non-Voltage-Gated 1, Gamma Subunit Gene - Sodium Channel, Nonvoltage-Gated 1, Gamma Gene - Sodium Channel, Nonvoltage-Gated 1, Gamma Subunit Gene