CRTC1-TRIM11 Cutaneous Tumor

**Semantic type:** Neoplastic Process

**Definition:** A very rare malignant dermal tumor of uncertain differentiation that morphologically overlaps with clear cell sarcoma, exhibits partial melanocytic differentiation, and is characterized by the presence of CRTC1-TRIM11 gene fusion. It is composed of epithelioid to fusiform cells with pale cytoplasm and vesicular nuclei. It appears to behave less aggressively than melanoma and clear cell sarcoma, and only a minority of the published cases have shown regional or distant metastasis.

**Synonyms:** - CRTC1::TRIM11 Cutaneous Tumor - CTCT - Cutaneous Melanocytic Tumor with CRTC1-TRIM11 Fusion - Cutaneous Melanocytic Tumor with CRTC1::TRIM11 Fusion - TRIM11 Melanocytoma