Tridolgosir Hydrochloride

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An orally-active synthetic hydrochloride salt form of swainsonine, an inhibitor of Golgi alpha-mannosidase II. Tridolgosir inhibits formation of carbohydrate structures affecting cell-cell adhesion, resulting in decreases in tumor growth or metastasis. This agent also stimulates the immune system. (NCI04)

**Synonyms:** - (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol Hydrochloride - GD-0039 - GD0039 - Swainsonine HCl - TRIDOLGOSIR HYDROCHLORIDE