WWTR1/FOSB Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal rearrangement that fuses exon 4 of the WWTR1 gene on the long arm of chromosome 3 in frame with exon 2 of the FOSB gene on the long arm of chromosome 19. This rearrangement is associated with pseudomyogenic hemangioendothelioma and deregulation of protein fosB transcriptional activation activity.

**Synonyms:** - WW Domain Containing Transcription Regulator 1/FosB Proto-Oncogene Fusion Gene - WW Domain Containing Transcription Regulator 1::FosB Proto-Oncogene Fusion Gene - WWTR1-FOSB Fusion Gene - WWTR1::FOSB Fusion Gene