CLTC/FOSB Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal rearrangement that fuses exon 17 of the CLTC gene on the long arm of chromosome 17 in frame with exon 2 of the FOSB gene on the long arm of chromosome 19. This rearrangement is associated with pseudomyogenic hemangioendothelioma and deregulation of protein fosB transcriptional activation activity.

**Synonyms:** - CLTC-FOSB Fusion Gene - CLTC::FOSB Fusion Gene - Clathrin Heavy Chain/FosB Proto-Oncogene Fusion Gene - Clathrin Heavy Chain::FosB Proto-Oncogene Fusion Gene