Treg Inhibitor GIM-531

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable small molecule inhibitor of regulatory T-cells (Tregs), with potential immunomodulatory and antineoplastic activities. Upon oral administration, Treg inhibitor GIM-531 inhibits the activity of immune suppressive Tregs through an as of yet unknown mechanism of action. This may restore antitumor immune responses.

**Synonyms:** - GIM 531 - GIM-531 - GIM531