SLC12A3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SLC12A3 wild-type allele is located in the vicinity of 16q13 and is approximately 51 kb in length. This allele, which encodes solute carrier family 12 member 3 protein, is involved in ion reabsorption by the renal distal convoluted tubule. Mutations in the gene are associated with Gitelman syndrome.

**Synonyms:** - NCC - NCCT - NaCl Electroneutral Thiazide-Sensitive Cotransporter Gene - Sodium-Chloride Co-Transporter Gene - Sodium-Chloride Cotransporter Gene - Sodium-Chloride Cotransporter, Thiazide-Sensitive Gene - Solute Carrier Family 12 (Sodium/Chloride Transporter), Member 3 Gene - Solute Carrier Family 12 Member 3 wt Allele - TSC - Thiazide-Sensitive Na-Cl Cotransporter Gene