Solute Carrier Family 12 Member 3

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Solute carrier family 12 member 3 (1021 aa, ~113 kDa) is encoded by the human SLC12A3 gene. This protein plays a role in sodium and chloride reabsorption by distal convoluted tubules in the kidneys.

**Synonyms:** - NCC - Na-Cl Cotransporter - Na-Cl Symporter - SLC12A3 - Thiazide-Sensitive Na-Cl Cotransporter - Thiazide-Sensitive Sodium-Chloride Cotransporter