Autologous CAR-engineered Regulatory T-cells SBT777101

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous T-regulatory cells (Tregs) that have been genetically modified to express a chimeric antigen receptor (CAR) targeting citrullinated proteins, with potential immunmodulating activity. Upon administration, the autologous CAR-engineered regulatory T-cells SBT777101 target and bind to citrullinated proteins and may decrease inflammation and promote immunologic homeostasis. Citrullinated proteins are found in inflamed disease-associated tissues in many autoimmune and inflammatory diseases.

**Synonyms:** - Autologous CAR-Tregs Cells SBT777101 - Autologous CAR-Tregs SBT-77-7101 - Autologous CAR-engineered Treg Cells SBT777101 - SBT 77 7101 - SBT-77-7101 - SBT-777101 - SBT77-7101 - SBT777101