Tetraspanin-8

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Tetraspanin-8 (237 aa, ~26 kDa) is encoded by the human TSPAN8 gene. This protein is involved in mTORC2 activation, integrin signaling and co-localization of proteases and substrates in tetraspanin-enriched microdomains.

**Synonyms:** - TSPAN8 - Tetraspanin 8 - Transmembrane 4 Superfamily Member 3 - Tspan-8 - Tumor-Associated Antigen CO-029